|
|
hexanoyl-CoA + malonyl-CoA + H+ <=> 3,5,7-trioxododecanoyl-CoA + CoA + CO2
|
2.3.1.206
3,5,7-trioxododecanoyl-CoA synthase
|
–
|
K
|
|
BRENDA:
BR50284
KEGG:
R10171
MetaCyc:
RXN-7852
|
|
|
|
hexanoate + ATP + CoA <=> hexanoyl-CoA + AMP + diphosphate
|
6.2.1.1
acetate---CoA ligase
6.2.1.12
4-coumarate---CoA ligase
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.3
long-chain-fatty-acid---CoA ligase
6.2.1.44
3-(methylthio)propionyl---CoA ligase
|
–
–
–
–
–
|
BM
|
|
BRENDA:
BR71
KEGG:
R00389
MetaCyc:
RXN-14172
SABIO-RK:
8094
|
|
|
|
hexanoyl-CoA + acetyl-CoA <=> 3-oxooctanoyl-CoA + CoA
|
2.3.1.155
acetyl-CoA C-myristoyltransferase
2.3.1.16
acetyl-CoA C-acyltransferase
|
–
–
|
MK
|
|
BRENDA:
BS189545
KEGG:
R04747
MetaCyc:
RXN-14277
SABIO-RK:
4403
|
|
|
|
hexanal + CoA + NAD+ <=> hexanoyl-CoA + NADH + H+
|
1.2.1
1.2.1.10
acetaldehyde dehydrogenase (acetylating)
1.2.1.57
butanal dehydrogenase
|
–
–
–
|
|
|
BRENDA:
BS258015
MetaCyc:
RXN-12568_WOP
SABIO-RK:
10854
|
|
|
|
hexanoyl-CoA + NAD+ <=> trans-2-hexenoyl-CoA + NADH + H+
|
1.3.1.44
trans-2-enoyl-CoA reductase (NAD+)
|
–
|
M
|
|
BRENDA:
BS258559-a
MetaCyc:
RXN-12559
SABIO-RK:
4406
|
|
|
|
hexanoyl-CoA + L-carnitine <=> (3R)-3-(hexanoyloxy)-4-(trimethylammonio)butanoate + CoA
|
2.3.1.137
carnitine O-octanoyltransferase
2.3.1.21
carnitine O-palmitoyltransferase
2.3.1.7
carnitine O-acetyltransferase
|
–
–
–
|
|
|
BRENDA:
BS320463;
BS451963
MetaCyc:
RXN-18369
|
|
|
|
hexanal + CoA + NADP+ <=> hexanoyl-CoA + NADPH + H+
|
1.2.1
1.2.1.76
succinate-semialdehyde dehydrogenase (acylating)
|
–
–
|
M
|
|
BRENDA:
BS404590
MetaCyc:
RXN-12568
|
|
|
|
hexanoyl-CoA + malonyl-CoA + H2O <=> 4-hydroxy-6-pentyl-2H-pyran-2-one + CoA + CO2 + H2O
|
2.3.1
2.3.1.233
1,3,6,8-tetrahydroxynaphthalene synthase
2.3.1.74
chalcone synthase
|
–
–
–
|
|
|
BRENDA:
BS430245
MetaCyc:
RXN-10688
|
|
|
|
trans-2-hexenoyl-CoA + NADPH <=> hexanoyl-CoA + NADP+
|
1.3.1.10
enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.38
trans-2-enoyl-CoA reductase (NADPH)
1.3.1.44
trans-2-enoyl-CoA reductase (NAD+)
1.3.1.8
acyl-CoA dehydrogenase (NADP+)
|
–
–
–
–
|
K
|
|
BRENDA:
BS258524
KEGG:
R06985
SABIO-RK:
7658
|
|
|
|
hexanoyl-CoA + FAD <=> trans-2-hexenoyl-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
1.3.8.1
short-chain acyl-CoA dehydrogenase
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
1.3.99
|
–
–
–
–
–
–
|
K
|
|
BRENDA:
BS414702
KEGG:
R04751
SABIO-RK:
4407
|
|
|
|
hexanoyl-CoA + O2 <=> trans-2-hexenoyl-CoA + H2O2
|
1.3.3.6
acyl-CoA oxidase
|
–
|
B
|
|
BRENDA:
BS258731
SABIO-RK:
9568
|
|
|
|
hexanoyl-CoA + acceptor <=> trans-2-hexenoyl-CoA + reduced_acceptor
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
1.3.99.12
2-methylacyl-CoA dehydrogenase
|
–
–
–
–
–
–
|
|
|
BRENDA:
BS258763
SABIO-RK:
6515
|
|
|
|
hexanoyl-CoA + sphingosine <=> CoA + N-hexanoyl-sphingenine
|
2.3.1.24
sphingosine N-acyltransferase
|
–
|
|
|
BRENDA:
BS320740
SABIO-RK:
10718
|
|
|
|
hexanoyl-CoA + H2O <=> CoA + hexanoate
|
2.3.1.16
acetyl-CoA C-acyltransferase
3.1.2.1
acetyl-CoA hydrolase
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
3.1.2.23
4-hydroxybenzoyl-CoA thioesterase
3.1.2.25
phenylacetyl-CoA hydrolase
|
–
–
–
–
–
–
|
B
|
|
BRENDA:
BS360739
SABIO-RK:
6591
|
|
|
|
hexanoyl-CoA + 2,6-dichlorophenolindophenol <=> trans-2-hexenoyl-CoA + reduced_2,6-dichlorophenolindophenol
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
–
|
|
|
BRENDA:
BS397426
SABIO-RK:
11494
|
|
|
|
hexanoyl-CoA + ferrocenium_hexafluorophosphate <=> trans-2-hexenoyl-CoA + ferrocenium_hexafluorophosphate
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
–
|
|
|
BRENDA:
BS451543
SABIO-RK:
6744
|
|
|
|
hexanoyl-CoA + 1,2-dipalmitoyl-sn-glycerol <=> CoA + 1,2-dipalmitoyl-3-hexanoyl_glycerol
|
2.3.1.20
diacylglycerol O-acyltransferase
|
–
|
|
|
BRENDA:
BS451942
SABIO-RK:
14158
|
|
|
|
4-coumaroyl-CoA + malonyl-CoA + hexanoyl-CoA + H2O <=> (1E,4Z)-5-hydroxy-1-(4-hydroxyphenyl)deca-1,4-dien-3-one + 3 CoA + 2 CO2
|
not assigned
|
–
|
K
|
|
KEGG:
R08796
|
|
|
|
feruloyl-CoA + malonyl-CoA + hexanoyl-CoA + H2O <=> 1-Dehydro-[6]-gingerdione + 3 CoA + 2 CO2
|
not assigned
|
–
|
K
|
|
KEGG:
R08797
|
|
|
|
hexanoyl-CoA + malonyl-CoA + H+ <=> olivetol + CoA + CO2
|
2.3.1
|
–
|
|
|
MetaCyc:
RXN-10687
|
|
|
|
H+ + hexanoyl-CoA + malonyl-CoA <=> 4-hydroxy-6-(2-oxoheptyl)-2H-pyran-2-one + CoA + CO2
|
2.3.1
|
–
|
|
|
MetaCyc:
RXN-10689
|
|
|
|
hexanoyl-CoA + malonyl-CoA + H+ <=> 3,5-dioxodecanoyl-CoA + CoA + CO2
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13662
|
|
|
|
hexanoyl-CoA + oxidized_electron_transfer_flavoprotein + H+ <=> trans-2-hexenoyl-CoA + reduced_flavodoxin
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
|
M
|
|
MetaCyc:
RXN-14278
|
|
|
|
hexanoyl-CoA + cholesterol <=> cholesteryl_hexanoate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
MetaCyc:
RXN-20224
|
|
|
|
hexanoyl-CoA + L-arginine <=> N-[(4S)-4-amino-5-oxodecyl]guanidine + CO2 + CoA
|
2.3.1.47
8-amino-7-oxononanoate synthase
|
–
|
|
|
BRENDA:
BS455768
|
|
|
|
hexanoyl-CoA + phosphate <=> CoA + hexanoyl_phosphate
|
2.3.1.19
phosphate butyryltransferase
|
–
|
|
|
BRENDA:
BS455769
|
|
|
|
hexanoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxyhexanoyl-CoA + succinate + CO2
|
1.14.11.18
phytanoyl-CoA dioxygenase
|
–
|
|
|
BRENDA:
BS376948
|
|
|
|
hexanoyl-CoA + flavin <=> trans-2-hexenoyl-CoA + reduced_flavodoxin
|
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
–
–
|
|
|
BRENDA:
BR36852
|
|
|
|
hexanoyl-CoA + butyryl-CoA <=> Phlorobutyrophenone + Phlorocaprophenone
|
2.3.1.74
chalcone synthase
|
–
|
|
|
BRENDA:
BS456065
|
|
|
|
hexanoyl-CoA + ferrocenium_hexafluorophosphate <=> trans-2-hexenoyl-CoA + reduced_ferrocenium_hexafluorophosphate
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS453889
|
|
|
|
hexanoyl-CoA + 2-O-[alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-D-glycerate <=> 2-O-[6-O-hexanoyl-alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-D-glycerate + CoA
|
2.3.1.273
diglucosylglycerate octanoyltransferase
|
–
|
|
|
BRENDA:
BS445546
|
|
|
|
hexanoyl-CoA + 2-hydroxy-amino-6-methyldipyrido[1,2-a:_3'',2''-d]imidazole <=> CoA + N-hexanoyloxyamino-6-methyldipyrido[1,2-a:_3'',2''-d]imidazole
|
2.3.1.118
N-hydroxyarylamine O-acetyltransferase
|
–
|
|
|
BRENDA:
BS320356
|
|
|
|
hexanoyl-CoA + ferricenium <=> trans-2-hexenoyl-CoA + Ferrocene
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS451544
|
|
|
|
hexanoyl-CoA + Meldola''s_Blue <=> trans-2-hexenoyl-CoA + reduced_meldola_blue
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS260379
|
|
|
|
hexanoyl-CoA + [acyl-carrier_protein] <=> CoA + hexanoyl-[acyl-carrier_protein]
|
2.3.1.38
[acyl-carrier-protein] S-acetyltransferase
|
–
|
|
|
BRENDA:
BS320849
|
|
|
|
hexanoyl-CoA + 1-butanol <=> CoA + butyl_hexanoate
|
2.3.1.84
alcohol O-acetyltransferase
|
–
|
|
|
BRENDA:
BS420771
|
|
|
|
hexanoyl-CoA + histamine <=> CoA + N-hexanoylhistamine
|
2.3.1.87
aralkylamine N-acetyltransferase
|
–
|
|
|
BRENDA:
BS435529
|
|
|
|
trans-2-hexenoyl-CoA + reduced_flavodoxin <=> hexanoyl-CoA + electron_transfer_protein
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS370164
|
|
|
|
hexanoyl-CoA + methylmalonyl-CoA <=> 4-hydroxy-3,5-dimethyl-6-pentyl-pyran-2-one + CoA + CO2
|
2.3.1.74
chalcone synthase
|
–
|
|
|
BRENDA:
BS379948
|
|
|
|
methylmalonyl-CoA + hexanoyl-CoA <=> triketide_lactone + 6-ethyl-4-hydroxy-3,5-dimethyl-2-pyrone
|
2.3.1.74
chalcone synthase
|
–
|
|
|
BRENDA:
BS454742
|
|
|
|
hexanoyl-CoA + malonyl-[acyl-carrier_protein] <=> 3-oxooctanoyl-[acyl-carrier_protein] + CoA + CO2
|
2.3.1.180
beta-ketoacyl-[acyl-carrier-protein] synthase III
|
–
|
|
|
BRENDA:
BS382022
|
|
|
|
hexanoyl-CoA + [Wnt]-L-serine <=> CoA + [Wnt]-O-hexanoyl-L-serine
|
2.3.1.250
[Wnt protein] O-palmitoleoyl transferase
|
–
|
|
|
BRENDA:
BS455771
|
|
|
|
hexanoyl-CoA + cinnamyl_alcohol <=> CoA + cinnamyl_hexanoate
|
2.3.1.84
alcohol O-acetyltransferase
|
–
|
|
|
BRENDA:
BS420772
|
|
|
|
hexanoyl-CoA + tetrazolium_salt <=> trans-2-hexenoyl-CoA + reduced_tetrazolium_salt
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS451546
|
|
|
|
hexanoylcarnitine + CoA <=> hexanoyl-CoA + carnitine
|
2.3.1.7
carnitine O-acetyltransferase
|
–
|
|
|
BRENDA:
BS321231
|
|
|
|
hexanoyl-CoA <=> 4-hydroxy-6-pentyl-2H-pyran-2-one + 4-hydroxy-6-(2''-oxoheptyl)-2-pyrone + CoA + CO2 + H2O
|
2.3.1.233
1,3,6,8-tetrahydroxynaphthalene synthase
2.3.1.253
phloroglucinol synthase
|
–
–
|
|
|
BRENDA:
BS430246
|
|
|
|
acetyl-CoA + hexanoate <=> acetate + hexanoyl-CoA
|
2.8.3.1
propionate CoA-transferase
|
–
|
|
|
BRENDA:
BS436982
|
|
|
|
hexanoyl-CoA + 5 malonyl-CoA + 5 (S)-methylmalonyl-CoA + 22 NADPH + 22 H+ <=> a_mycoketide-CoA + 10 CO2 + 10 CoA + 22 NADP+ + 11 H2O
|
2.3.1.295
mycoketide-CoA synthase
|
–
|
|
|
BRENDA:
BR52917
|
|
|
|
trans-2-hexenoyl-CoA + NADH <=> hexanoyl-CoA + NADP+
|
1.3.1.8
acyl-CoA dehydrogenase (NADP+)
|
–
|
|
|
BRENDA:
BS258633-a
|
|
|
|
hexanoyl-CoA + ethanol <=> CoA + ethyl_hexanoate
|
2.3.1.84
alcohol O-acetyltransferase
|
–
|
|
|
BRENDA:
BS420773
|
|
|
|
hexanoyl-CoA + glycine <=> CoA + N-hexanoylglycine
|
2.3.1.13
glycine N-acyltransferase
|
–
|
|
|
BRENDA:
BS435528
|
|
|
|
3 malonyl-CoA + hexanoyl-CoA <=> 4 CoA + phloroglucinol + 3 CO2
|
2.3.1.159
acridone synthase
|
–
|
|
|
BRENDA:
BS435072
|
|
|
|
malonyl-CoA + hexanoyl-CoA <=> Phlorocaprophenone + CO2 + CoA
|
2.3.1.74
chalcone synthase
|
–
|
|
|
BRENDA:
BS321289
|
|
|
|
hexanoyl-CoA + malonyl-CoA <=> bisnoryangonin-type_and_p-coumaroyltriacetic_acid_lactone-type_pyrones + CoA + CO2
|
2.3.1.95
trihydroxystilbene synthase
|
–
|
|
|
BRENDA:
BS321511
|
|
|
|
3 malonyl-CoA + hexanoyl-CoA <=> 4 CoA + 4-hydroxy-6-pentyl-2H-pyran-2-one + 4-hydroxy-6-(2-oxoheptyl)-2H-pyran-2-one + 3 CO2
|
2.3.1.220
2,4,6-trihydroxybenzophenone synthase
|
–
|
|
|
BRENDA:
BS422490
|
|
|
|
3 malonyl-CoA + hexanoyl-CoA <=> 4 CoA + 4-hydroxy-6-pentyl-2H-pyran-2-one + 5-hexanoyl-4-hydroxy-6-methyl-2H-pyran-2-one + 3 CO2
|
2.3.1.151
2,3',4,6-tetrahydroxybenzophenone synthase
|
–
|
|
|
BRENDA:
BS419946
|
|
|
|
hexanoyl-CoA + malonyl-CoA <=> 6-pentyl_triacetic_acid_lactone + CoA
|
2.3.1.165
6-methylsalicylic-acid synthase
|
–
|
|
|
BRENDA:
BS320580
|
|
|
|
hexanoyl-CoA + phenazine_methosulfate + 2,6-dichlorophenolindophenol <=> trans-2-hexenoyl-CoA + reduced_acceptor
|
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS258833
|
|
|
|
hexanoyl-CoA + flavin <=> trans-2-hexenoyl-CoA + reduced_acceptor
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS258790
|
|
|
|
hexanoyl-CoA + phenazine_methosulfate + oxidized_2,6-dichlorophenolindophenol <=> trans-2-hexenoyl-CoA + reduced_acceptor
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS258791
|
|
|
|
hexanoyl-CoA + electron_acceptor <=> trans-2-hexenoyl-CoA + reduced_acceptor
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS388884
|
|
|
|
hexanoyl-CoA + 1-alkyl-2-lyso-sn-glycero-3-phosphocholine <=> 2-hexanoyl-1-alkyl-sn-glycero-3-phosphocholine
|
2.3.1.67
1-alkylglycerophosphocholine O-acetyltransferase
|
–
|
|
|
BRENDA:
BS451961
|
|
|
|
hexanoyl-CoA + methanol <=> CoA + methyl_caproate
|
2.3.1.84
alcohol O-acetyltransferase
|
–
|
|
|
BRENDA:
BS420774
|
|
|
|
ATP + hexanoate + CoA <=> ADP + phosphate + hexanoyl-CoA
|
6.2.1.13
acetate---CoA ligase (ADP-forming)
|
–
|
|
|
BRENDA:
BS443144
|
|
|
|
hexanoyl-CoA + phenazine_methosulfate <=> trans-2-hexenoyl-CoA + reduced_phenazine_methosulfate
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS260362
|
|
|
|
hexanoyl-CoA + L-carnitine <=> hexanoylcarnitine + CoA
|
2.3.1.7
carnitine O-acetyltransferase
|
–
|
|
|
SABIO-RK:
6692
|
|
|
|
2n 2n_2n_NADPH + H+ + n n_n_Malonyl-CoA + hexanoyl-CoA <=> 2n 2n_2n_NADP+ + fatty_acid + CoA + n n_n_CO2
|
2.3.1.85
fatty-acid synthase system
2.3.1.86
fatty-acyl-CoA synthase system
|
–
–
|
|
|
SABIO-RK:
10053
|
|